Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13727493 | 0.80 | CA2 (0.58) | CA2CAMK2ALMNAAKR1B1FNTA | |
| SCHEMBL560200 | 0.78 | TPMT (0.38) | CA2CAMK2A | |
| SCHEMBL17802296 | 0.78 | MEN1 (0.46) | LMNAGAAHTTKMT2AHPGD | |
| SCHEMBL11519547 | 0.78 | NPC1 (0.48) | LMNAHTTKMT2AALDH1A1HPGD | |
| SCHEMBL9065640 | 0.78 | CTBP2 (0.48) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL17802304 | 0.78 | ALDH1A1 (0.48) | CA2LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL6451970 | 0.78 | GAA (0.50) | CA2LMNAGAAHTTKMT2A | |
| SCHEMBL25169 | 0.77 | CES1 (0.58) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL15309802 | 0.77 | ALDH1A1 (0.52) | CA2GAATSHRPTGS1ANPEP | |
| Water SCHEMBL17802313 | 0.77 | GAA (0.48) | CA2LMNAGAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202243-A1 | IN Vivo Incorporation of Unnatural Amino Acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-09 | — | — | US | disclosed |