Quinmerac

Quinmerac

SCHEMBL9065652

Cc1cnc2c(C(=O)O)c(Cl)ccc2c1.c1ccc2ncccc2c1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 1/20 0.51
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP1A2 P05177 1/20 0.44
DOT1L Q8TEK3 1/20 0.43
PARP1 P09874 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KDR P35968 1/20 0.40
DHODH Q02127 2/20 0.39
PSMD14 O00487 1/20 0.38
COPS5 Q92905 1/20 0.38
MGAM O43451 1/20 0.38
NPC1 O15118 1/20 0.38
HCRTR1 O43613 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinmerac SCHEMBL16592782 0.87 MGAM (0.52) ALKCCR1CCR5CCR8CYP1A2
Quinmerac SCHEMBL8539662 0.86 ALK (0.60) ALKCCR1CCR5CCR8PARP1
Quinmerac SCHEMBL54128 0.86 ALK (0.60) ALKCCR1CCR5CCR8PARP1
Quinmerac SCHEMBL29351452 0.86 ALK (0.60) ALKCCR1CCR5CCR8PARP1
Quinmerac SCHEMBL29433226 0.86 ALK (0.60) ALKCCR1CCR5CCR8PARP1
Quinmerac SCHEMBL28348267 0.82 ALK (0.56) ALKCCR1CCR5CCR8PARP1
Quinmerac SCHEMBL5267957 0.81 ALK (0.55) ALKCCR1CCR5CCR8PARP1
Quinmerac SCHEMBL28857862 0.79 ALK (0.51) ALKCCR1CCR5CCR8PARP1
Quinmerac SCHEMBL14655402 0.77 PKM (0.53) ALKCCR1CCR5CCR8KDM4E
SCHEMBL9197665 0.77 ALDH1A1 (0.54) ALKCCR1CCR5CCR8DOT1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711112-A1 HERBICIDE COMPOSITION, ACTIVITY-PROMOTING AGENT FOR IMPROVING THE EFFICACY OF THE HERBICIDE, AND A METHOD FOR TREATING CULTIVATED PLANTS KEMIRA OY (FI) 1996-05-15 EP disclosed
WO-1995003697-A1 HERBICIDE COMPOSITION, ACTIVITY-PROMOTING AGENT FOR IMPROVING THE EFFICACY OF THE HERBICIDE, AND A METHOD FOR TREATING CULTIVATED PLANTS KEMIRA OY (FI) 1995-02-09 WO disclosed