SCHEMBL9197665

SCHEMBL9197665

O=C(O)c1c(Cl)ccc2cccnc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
ALK Q9UM73 1/20 0.54
LMNA P02545 4/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MMP2 P08253 2/20 0.50
TSHR P16473 2/20 0.50
GMNN O75496 1/20 0.50
TP53 P04637 1/20 0.50
HSP90AA1 P07900 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MMP9 P14780 1/20 0.50
ALOX15 P16050 1/20 0.50
NFKB1 P19838 1/20 0.50
MMP8 P22894 1/20 0.50
CCR1 P32246 1/20 0.50
THPO P40225 1/20 0.50
MTOR P42345 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29906219 0.81 ALDH1A1 (0.70) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL31057838 0.81 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL16040593 0.81 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL69869 0.81 ALDH1A1 (0.70) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL27908512 0.79 ALDH1A1 (0.54) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL11430231 0.79 LMNA (0.56) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL4076198 0.79 ALDH1A1 (0.54) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL13516424 0.76 ALDH1A1 (0.68) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL9207272 0.76 ALDH1A1 (0.46) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL3756602 0.76 SLC40A1 (0.52) ALDH1A1LMNAKDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116969887-A Preparation process of intermediate 7-chloro 8-quinolinic acid and synthesis process of quinclorac 启农生物科技(北京)有限公司 2023-10-31 CN claimed
CN-115124465-B Preparation method of quinclorac intermediate 定远县嘉禾植物保护剂有限责任公司 2023-03-14 CN claimed
CN-115124465-A Preparation method of quinclorac intermediate 定远县嘉禾植物保护剂有限责任公司 2022-09-30 CN claimed
CN-111377863-B Preparation method of 7-chloro-8-quinoline carboxylic acid 北京颖泰嘉和生物科技股份有限公司 2021-06-08 CN claimed
CN-111377862-B Preparation method of quinclorac 北京颖泰嘉和生物科技股份有限公司 2021-06-08 CN claimed
CN-111377862-A Preparation method of quinclorac 北京颖泰嘉和生物科技股份有限公司 2020-07-07 CN claimed
CN-111377863-A Preparation method of 7-chloro-8-quinoline carboxylic acid 北京颖泰嘉和生物科技股份有限公司 2020-07-07 CN claimed
EP-0513056-B1 PROCESS FOR PURIFYING 7-CHLOR-QUINOLINE-8-CARBOXYLIC ACIDS BASF AG (DE) 1995-11-29 EP claimed
US-5310915-A Rerystallization from lower alcohols miscible with water in presence of base BASF AKTIENGESELLSCHAFT (DE) 1994-05-10 US claimed
EP-0513056-A1 PROCESS FOR PURIFYING 7-CHLOR-QUINOLINE-8-CARBOXYLIC ACIDS. BASF AG (DE) 1992-11-19 EP claimed
WO-1991011436-A1 PROCESS FOR PURIFYING 7-CHLOR-QUINOLINE-8-CARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 1991-08-08 WO claimed
US-5006659-A Preparation of 7-chloroquinoline-8-carboxylic acids BASF AKTIENGESELLSCHAFT (DE) 1991-04-09 US claimed
EP-0270889-B1 USE OF 7-CHLOROQUINOLINE-8-CARBOXYLIC ACIDS FOR INFLUENCING THE DEVELOPMENT OF CROPS BASF Aktiengesellschaft (DE) 1990-05-09 EP claimed
US-4857103-A Influencing the development of crops with 7-chloroquinoline-8-carboxylic acids BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US claimed
EP-0270889-A1 Use of 7-chloroquinoline-8-carboxylic acids for influencing the development of crops BASF Aktiengesellschaft (DE) 1988-06-15 EP claimed
CN-114994201-B Method for detecting impurities in quinclorac 江苏恒生检测有限公司 2024-07-23 CN disclosed
CN-116969887-A Preparation process of intermediate 7-chloro 8-quinolinic acid and synthesis process of quinclorac 启农生物科技(北京)有限公司 2023-10-31 CN disclosed
EP-0282778-A1 Process for the preparation of 7-chloro-quinoline-8-carboxylic acids BASF Aktiengesellschaft (DE) 1988-09-21 EP disclosed
EP-0282778-A1 Process for the preparation of 7-chloro-quinoline-8-carboxylic acids BASF Aktiengesellschaft (DE) 1988-09-21 EP disclosed
EP-0270889-A1 Use of 7-chloroquinoline-8-carboxylic acids for influencing the development of crops BASF Aktiengesellschaft (DE) 1988-06-15 EP disclosed