Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650618 | 0.79 | TSHR (0.35) | ALDH1A1CA2NFKB1 | |
| SCHEMBL1905411 | 0.75 | MEN1 (0.39) | ALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL11332306 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4ECA2PTGS1MMP12 | |
| SCHEMBL8766351 | 0.71 | NPC1 (0.37) | ALDH1A1 | |
| SCHEMBL11404809 | 0.71 | ZDHHC20 (0.32) | ZDHHC20ZDHHC2 | |
| SCHEMBL321022 | 0.69 | — | — | |
| SCHEMBL451023 | 0.69 | KDM4E (0.41) | ALDH1A1KDM4ECA2PTGS1MMP12 | |
| SCHEMBL450522 | 0.69 | KDM4E (0.41) | ALDH1A1KDM4ECA2PTGS1MMP12 | |
| SCHEMBL27617828 | 0.67 | — | — | |
| SCHEMBL2987964 | 0.65 | KDM4E (0.44) | ALDH1A1KDM4ECA2PTGS1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108753198-B | Adhesion promoter for silicone sealant, preparation method of adhesion promoter, silicone sealant applied to ballastless track and preparation method of silicone sealant | 株洲飞鹿高新材料技术股份有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-111592855-A | High-temperature elastic weather-resistant adhesive and preparation method and process thereof | 宁波大大防腐材料技术有限公司 | 2020-08-28 | — | — | CN | disclosed |
| EP-0591622-B1 | Room-temperature curable polyorganosiloxane composition | TOSHIBA SILICONE (JP) | 1996-11-20 | — | — | EP | disclosed |
| US-5371164-A | Blend with a polysilazane | TOSHIBA SILICONE CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0591622-A1 | Room-temperature curable polyorganosiloxane composition | TOSHIBA SILICONE CO., LTD. (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5246980-A | Anhydrous endblocked polysiloxane, diacetamidosilane chain extender and eminoxysilicone compound crosslinker in first part; endbocked polysiloxanes in second part | DOW CORNING CORPORATION (US) | 1993-09-21 | — | — | US | disclosed |