Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065756 | 1.00 | LMNA (0.38) | LMNACYP2A6MAOBMAOAHPGD | |
| SCHEMBL5612605 | 0.87 | LMNA (0.39) | LMNACA1CA2CA9CYP3A4 | |
| SCHEMBL535420 | 0.80 | LMNA (0.42) | LMNACYP2A6MAOBMAOAHPGD | |
| SCHEMBL9133041 | 0.80 | ESR2 (0.36) | LMNAMAOBCA1CA2CA9 | |
| SCHEMBL11136720 | 0.76 | TDP1 (0.48) | MAOBMAOAHPGDMEN1KMT2A | |
| SCHEMBL3791268 | 0.76 | CYP2A6 (0.38) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL11136726 | 0.76 | TDP1 (0.48) | MAOBMAOAHPGDMEN1KMT2A | |
| SCHEMBL30046823 | 0.76 | NFE2L2 (0.43) | LMNAMAOBMAOACYP3A4CYP1A2 | |
| SCHEMBL9216513 | 0.76 | MEN1 (0.46) | LMNAHPGDMEN1KMT2ACA1 | |
| SCHEMBL5898125 | 0.75 | CA4 (0.43) | LMNAMAOAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489517-B1 | Stabilised polyketone composition | BP CHEM INT LTD (GB) | 1996-12-27 | — | — | EP | claimed |