Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065835 | 0.92 | LMNA (0.54) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1021824 | 0.89 | LMNA (0.60) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9696748 | 0.89 | LMNA (0.51) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15071452 | 0.87 | LMNA (0.49) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14085637 | 0.85 | LMNA (0.48) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL25602128 | 0.83 | LMNA (0.44) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14085638 | 0.83 | LMNA (0.46) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14887276 | 0.81 | LMNA (0.44) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1952587 | 0.80 | LMNA (0.55) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20629443 | 0.80 | LMNA (0.49) | LMNAMAPK1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0130680-A2 | Cure to elastomers composition | LOCTITE CORPORATION (US) | 1985-01-09 | — | — | EP | claimed |
| US-4439600-A | Cure to elastomers compositions | LOCTITE CORPORATION (US) | 1984-03-27 | — | — | US | claimed |
| EP-0383842-B1 | STABILIZED POLYMERIZABLE COMPOSITIONS | LOCTITE CORP (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5096963-A | In a crystal matrix, storage stability, adhesives, coatings, sealants | LOCTITE CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0383842-A4 | STABILIZED POLYMERIZABLE COMPOSITIONS | — | 1990-10-24 | — | — | EP | disclosed |
| EP-0383842-A1 | STABILIZED POLYMERIZABLE COMPOSITIONS. | LOCTITE CORP (US) | 1990-08-29 | — | — | EP | disclosed |
| WO-1989007623-A1 | STABILIZED POLYMERIZABLE COMPOSITIONS | LOCTITE CORPORATION (US) | 1989-08-24 | — | — | WO | disclosed |
| EP-0114117-B1 | RAPID CURE ACRYLIC MONOMER SYSTEMS | LOCTITE CORPORATION (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4574138-A | FREE RADICAL CATALYST, URETHANE ACRYLATE | LOCTITE CORPORATION A CT CORP | 1986-03-04 | — | — | US | disclosed |
| EP-0130680-A2 | Cure to elastomers composition | LOCTITE CORPORATION (US) | 1985-01-09 | — | — | EP | disclosed |
| EP-0114117-A1 | Rapid cure acrylic monomer systems | LOCTITE CORPORATION (US) | 1984-07-25 | — | — | EP | disclosed |
| US-4439600-A | Cure to elastomers compositions | LOCTITE CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |