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Sugi Predict / Compounds / SCHEMBL15071452

SCHEMBL15071452

SCHEMBL15071452

C=C(C)C(=O)OCCOC(=O)Nc1cc(NC(C)=O)ccc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.49
▸ ALDH1A1 P00352 2/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ KMT2A Q03164 2/20 0.46
▸ SMN1; SMN2 Q16637 6/20 0.43
▸ NPC1 O15118 3/20 0.43
▸ RAB9A P51151 3/20 0.43
▸ HPGD P15428 2/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ NLRP3 Q96P20 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ ATM Q13315 1/20 0.39
▸ EGFR P00533 2/20 0.39
▸ KDR P35968 2/20 0.39
▸ ABL1 P00519 1/20 0.38
▸ PDGFRB P09619 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065835 0.95 LMNA (0.54) LMNAALDH1A1MAPK1KMT2ASMN1; SMN2
SCHEMBL9696748 0.91 LMNA (0.51) LMNAALDH1A1MAPK1KMT2ASMN1; SMN2
SCHEMBL14085637 0.88 LMNA (0.48) LMNAALDH1A1MAPK1KMT2ASMN1; SMN2
SCHEMBL9065826 0.87 LMNA (0.50) LMNAALDH1A1MAPK1SMN1; SMN2NPC1
SCHEMBL14085638 0.85 LMNA (0.46) LMNAALDH1A1MAPK1SMN1; SMN2NPC1
SCHEMBL14887276 0.84 LMNA (0.44) LMNAALDH1A1MAPK1SMN1; SMN2NPC1
SCHEMBL811637 0.83 NLRP3 (0.56) LMNAALDH1A1MAPK1KMT2ASMN1; SMN2
SCHEMBL24121572 0.82 HPGD (0.45) LMNAALDH1A1MAPK1KMT2ASMN1; SMN2
SCHEMBL16318074 0.81 LMNA (0.52) LMNAALDH1A1MAPK1KMT2ASMN1; SMN2
SCHEMBL25602128 0.81 LMNA (0.44) LMNAALDH1A1MAPK1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9815922-B2 Method for producing end-modified polybutadiene or end-modified hydrogenated polybutadiene and composition containing same NIPPON SODA CO., LTD. (JP) 2017-11-14 — — US disclosed
US-9815922-B2 Method for producing end-modified polybutadiene or end-modified hydrogenated polybutadiene and composition containing same NIPPON SODA CO., LTD. (JP) 2017-11-14 — — US disclosed
US-20150240009-A1 METHOD FOR PRODUCING END-MODIFIED POLYBUTADIENE OR END-MODIFIED HYDROGENATED POLYBUTADIENE AND COMPOSITION CONTAINING SAME NIPPON SODA CO., LTD. (JP) 2015-08-27 — — US disclosed
US-20150240009-A1 METHOD FOR PRODUCING END-MODIFIED POLYBUTADIENE OR END-MODIFIED HYDROGENATED POLYBUTADIENE AND COMPOSITION CONTAINING SAME NIPPON SODA CO., LTD. (JP) 2015-08-27 — — US disclosed
US-8822600-B2 Method for producing terminal acrylic-modified polybutadiene or terminal acrylic-modified hydrogenated polybutadiene, and composition containing same NIPPON SODA CO., LTD. (JP) 2014-09-02 — — US disclosed
US-8822600-B2 Method for producing terminal acrylic-modified polybutadiene or terminal acrylic-modified hydrogenated polybutadiene, and composition containing same NIPPON SODA CO., LTD. (JP) 2014-09-02 — — US disclosed
EP-2620455-A1 METHOD FOR PRODUCING TERMINAL ACRYLIC-MODIFIED POLYBUTADIENE OR TERMINAL ACRYLIC-MODIFIED HYDROGENATED POLYBUTADIENE, AND COMPOSITION CONTAINING SAME Nippon Soda Co., Ltd. (JP) 2013-07-31 — — EP disclosed
US-20130165586-A1 METHOD FOR PRODUCING TERMINAL ACRYLIC-MODIFIED POLYBUTADIENE OR TERMINAL ACRYLIC-MODIFIED HYDROGENATED POLYBUTADIENE, AND COMPOSITION CONTAINING SAME NIPPON SODA CO., LTD. (JP) 2013-06-27 — — US disclosed
US-20130165586-A1 METHOD FOR PRODUCING TERMINAL ACRYLIC-MODIFIED POLYBUTADIENE OR TERMINAL ACRYLIC-MODIFIED HYDROGENATED POLYBUTADIENE, AND COMPOSITION CONTAINING SAME NIPPON SODA CO., LTD. (JP) 2013-06-27 — — US disclosed