SCHEMBL9065835

SCHEMBL9065835

C=C(C)C(=O)OCCOC(=O)Nc1ccc(C)c(NC(=O)OCCOC(=O)C(=C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.54
ALDH1A1 P00352 3/20 0.54
MAPK1 P28482 1/20 0.54
HPGD P15428 4/20 0.48
RAB9A P51151 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
NPC1 O15118 3/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C9 P11712 3/20 0.48
CYP2C19 P33261 3/20 0.48
NLRP3 Q96P20 1/20 0.48
KMT2A Q03164 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
ATM Q13315 1/20 0.40
EGFR P00533 2/20 0.40
KDR P35968 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9696748 0.96 LMNA (0.51) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL15071452 0.95 LMNA (0.49) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL14085637 0.93 LMNA (0.48) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL9065826 0.92 LMNA (0.50) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL14085638 0.90 LMNA (0.46) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL14887276 0.88 LMNA (0.44) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL24121572 0.86 HPGD (0.45) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL16318074 0.86 LMNA (0.52) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL25602128 0.85 LMNA (0.44) LMNAALDH1A1MAPK1HPGDRAB9A
SCHEMBL13925067 0.84 ALDH1A1 (0.41) LMNAALDH1A1MAPK1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383842-B1 STABILIZED POLYMERIZABLE COMPOSITIONS LOCTITE CORP (US) 1996-07-24 EP disclosed
EP-0383842-A4 STABILIZED POLYMERIZABLE COMPOSITIONS 1990-10-24 EP disclosed
EP-0383842-A1 STABILIZED POLYMERIZABLE COMPOSITIONS. LOCTITE CORP (US) 1990-08-29 EP disclosed
WO-1989007623-A1 STABILIZED POLYMERIZABLE COMPOSITIONS LOCTITE CORPORATION (US) 1989-08-24 WO disclosed
US-4500629-A Method of forming images from liquid masses CIBA-GEIGY CORPORATION (US) 1985-02-19 US disclosed