4-Nitrotoluene

4-Nitrotoluene

SCHEMBL9065867

Cc1ccc(N)cc1.Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.78
ACHE P22303 3/20 0.78
HSD17B10 Q99714 2/20 0.78
KMT2A Q03164 3/20 0.62
MEN1 O00255 2/20 0.62
MAPT P10636 1/20 0.62
ESR1 P03372 2/20 0.58
CYP19A1 P11511 2/20 0.58
ESR2 Q92731 2/20 0.58
CYP3A4 P08684 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
TSHR P16473 4/20 0.52
PKM P14618 1/20 0.50
KDM4E B2RXH2 1/20 0.49
NPC1 O15118 1/20 0.49
GAA P10253 1/20 0.49
THRB P10828 1/20 0.49
ALOX12 P18054 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Nitroaniline SCHEMBL4208296 0.89 ALDH1A1 (0.90) ALDH1A1ACHEHSD17B10KMT2AMEN1
4-Nitrotoluene SCHEMBL11816835 0.89 ACHE (0.90) ALDH1A1ACHEHSD17B10CYP3A4TDP1
4-Nitrotoluene SCHEMBL10336129 0.89 ACHE (0.90) ALDH1A1ACHEHSD17B10CYP3A4TDP1
4-Nitrotoluene SCHEMBL2484690 0.89 ACHE (1.00) ALDH1A1ACHEHSD17B10KMT2AMAPT
4-Nitroaniline SCHEMBL16451 0.89 ALDH1A1 (1.00) ALDH1A1ACHEHSD17B10KMT2AMEN1
4-Nitrotoluene SCHEMBL73252 0.89 ACHE (1.00) ALDH1A1ACHEHSD17B10KMT2AMAPT
4-Nitroaniline SCHEMBL27963818 0.89 ALDH1A1 (1.00) ALDH1A1ACHEHSD17B10KMT2AMEN1
SCHEMBL9065915 0.89 ALDH1A1 (1.00) ALDH1A1ACHEHSD17B10KMT2AMEN1
4-Nitroaniline SCHEMBL13529022 0.89 ALDH1A1 (1.00) ALDH1A1ACHEHSD17B10KMT2AMEN1
Sulfanilamide SCHEMBL27822353 0.88 CA1 (0.70) ALDH1A1ACHEHSD17B10KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104593094-A High octane unleaded aviation gasoline SHELL INT RESEARCH 2015-05-06 CN disclosed
CN-104593096-A High octane unleaded aviation gasoline SHELL INT RESEARCH 2015-05-06 CN disclosed
CN-104593095-A High octane unleaded aviation gasoline SHELL INT RESEARCH 2015-05-06 CN disclosed
WO-1996037449-A1 METHOD FOR PREPARING ETHYLBENZENE FROM 4-VINYLCYCLOHEXENE KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 1996-11-28 WO disclosed