Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 1/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692574 | 0.92 | HSD17B7 (0.53) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL9066101 | 0.90 | HSD17B7 (0.52) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8077567 | 0.89 | HSD17B7 (0.54) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL4268268 | 0.82 | SHBG (0.62) | HSD17B7 | |
| SCHEMBL9214886 | 0.82 | HSD17B7 (0.58) | HSD17B7 | |
| SCHEMBL13656755 | 0.82 | SHBG (0.62) | HSD17B7 | |
| SCHEMBL4268271 | 0.82 | SHBG (0.62) | HSD17B7 | |
| SCHEMBL9214878 | 0.82 | HSD17B7 (0.58) | HSD17B7 | |
| SCHEMBL9066073 | 0.81 | HSD17B7 (0.47) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL9066169 | 0.79 | HSD17B7 (0.52) | HSD17B7SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641211-A1 | INHIBITORS OF TESTOSTERONE 5$g(a)-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1995-03-08 | — | — | EP | claimed |
| WO-1993023053-A1 | INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1993-11-25 | — | — | WO | claimed |
| US-5494914-A | USEFUL FOR TREATMENT OF DISEASES WHOSE PROGRESS IS AIDED BY ACTIVATION OF ANDROGEN RECEPTORS | ENDORECHERCHE (CA) | 1996-02-27 | — | — | US | disclosed |
| EP-0641211-A1 | INHIBITORS OF TESTOSTERONE 5$g(a)-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993023053-A1 | INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1993-11-25 | — | — | WO | disclosed |