SCHEMBL9066283

SCHEMBL9066283

CC1CCC(c2cc(Br)c(O)c(Br)c2)(c2cc(Br)c(O)c(Br)c2)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
ACHE P22303 1/20 0.39
CYP3A4 P08684 2/20 0.37
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
HIF1A Q16665 1/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
ESR2 Q92731 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065938 0.81 ALDH1A1 (0.37) ALDH1A1ACHECYP3A4TSHRTDP1
SCHEMBL9065670 0.81 ACHE (0.36) ALDH1A1ACHECYP3A4TSHRTDP1
SCHEMBL9075093 0.81 TSHR (0.40) ALDH1A1ACHECYP3A4TSHRTDP1
SCHEMBL9066255 0.80 ALDH1A1 (0.39) ALDH1A1ACHECYP3A4TSHRTDP1
SCHEMBL6857583 0.79 ACHE (0.63) ACHECYP2C9ESR2CA1CA2
SCHEMBL9066194 0.79 CYP2D6 (0.41) ALDH1A1ACHECYP3A4TSHRTDP1
SCHEMBL9066456 0.78 CRHBP (0.41) ESR2AKR1C1CRHBPCRHR2ESR1
SCHEMBL9067006 0.78 ACHE (0.39) ALDH1A1ACHECYP3A4TSHRTDP1
SCHEMBL9065754 0.78 CYP3A4 (0.37) ALDH1A1ACHECYP3A4TSHRTDP1
SCHEMBL8371595 0.76 ACHE (0.59) ALDH1A1ACHECYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469403-B1 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-B1 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-A2 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
EP-0469403-A2 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
EP-0413190-A2 Polycarbonates prepared from n-alkyl substituted cyclohexylidene diphenols BAYER AG (DE) 1991-02-20 EP disclosed