Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570551 | 0.86 | THRA (0.49) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL17353573 | 0.84 | THRA (0.56) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL3997456 | 0.84 | THRA (0.56) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL1605266 | 0.84 | LTB4R (0.40) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL31036387 | 0.84 | THRA (0.50) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL11609843 | 0.84 | THRA (0.50) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL9066512 | 0.82 | PLK1 (0.49) | THRATHRBPTGS2PLK1CETP | |
| SCHEMBL3929117 | 0.82 | THRA (0.53) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL4980580 | 0.82 | THRA (0.53) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL1001010 | 0.82 | THRA (0.53) | THRATHRBPPARAPPARGLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714398-A1 | GAMMA CRYSTALLINE MODIFICATION OF 2,2',2\"-NITRILO TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL)PHOSPHITE] | Ciba SC Holding AG (CH) | 1996-06-05 | — | — | EP | disclosed |
| EP-0674614-A1 | NOVEL LIQUID PHENOLIC ANTIOXIDANTS | Ciba SC Holding AG (CH) | 1995-10-04 | — | — | EP | disclosed |
| WO-1995005387-A1 | GAMMA CRYSTALLINE MODIFICATION OF 2,2',2'-NITRILO[TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL)PHOSPHITE] | CIBA-GEIGY AG (CH) | 1995-02-23 | — | — | WO | disclosed |
| WO-1994014748-A1 | NOVEL LIQUID PHENOLIC ANTIOXIDANTS | CIBA-GEIGY AG (CH) | 1994-07-07 | — | — | WO | disclosed |