SCHEMBL9066609

SCHEMBL9066609

Clc1ccc(C2=C([Zr]C3=C(c4ccc(Cl)cc4)C=CC3)CC=C2)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
LMNA P02545 1/20 0.32
CYP2A6 P11509 1/20 0.32
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7566925 0.98 CYP1A2 (0.32) CYP1A2LMNACYP2A6
Hydrochloric Acid SCHEMBL1073650 0.78 ALDH1A1 (0.32)
Fluoride SCHEMBL1130347 0.78 ALDH1A1 (0.32)
SCHEMBL9065742 0.76 KIF11 (0.39) LMNA
Hydrochloric Acid SCHEMBL7572285 0.74 KIF11 (0.38) LMNA
SCHEMBL7202227 0.72 CYP1A2 (0.38) CYP1A2LMNACYP2A6AHR
Hydrochloric Acid SCHEMBL7566921 0.71 CYP1A2 (0.32) CYP1A2LMNACYP2A6
Chlorobenzene SCHEMBL6209168 0.65 TSHR (0.41) CYP1A2
SCHEMBL9066357 0.65 DYRK1A (0.44) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL3682863 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540108-B1 Catalyst composition SHELL INT RESEARCH (NL) 1996-01-03 EP claimed