Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10383232 | 0.94 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Logran SCHEMBL9066883 | 0.92 | ALDH1A1 (0.55) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL54807 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL8535445 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL29373703 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL7902297 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL54874 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL11325389 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL29636275 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Logran SCHEMBL8535049 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |