Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066777 | 0.73 | SMN1; SMN2 (0.80) | SMN1; SMN2POLBMAPTMEN1THRB | |
| SCHEMBL10696332 | 0.73 | POLB (0.41) | SMN1; SMN2POLBMAPTMEN1KMT2A | |
| SCHEMBL11349823 | 0.71 | KMT2A (0.45) | SMN1; SMN2POLBMAPTMEN1THRB | |
| SCHEMBL9066778 | 0.68 | L3MBTL1 (0.46) | SMN1; SMN2POLBMAPTMEN1THRB | |
| SCHEMBL2534824 | 0.68 | GAA (0.48) | POLBMAPTMEN1KMT2ATP53 | |
| Iodide SCHEMBL5462956 | 0.68 | MEN1 (0.50) | SMN1; SMN2POLBMAPTMEN1THRB | |
| SCHEMBL14428043 | 0.66 | MEN1 (0.44) | SMN1; SMN2POLBMAPTMEN1THRB | |
| SCHEMBL16285343 | 0.66 | ALDH1A1 (0.41) | SMN1; SMN2POLBMAPTMEN1THRB | |
| SCHEMBL14341655 | 0.65 | SMN1; SMN2 (0.61) | SMN1; SMN2POLBMAPTKMT2ARAB9A | |
| SCHEMBL23524889 | 0.63 | SMN1; SMN2 (0.43) | SMN1; SMN2POLBMAPTTHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543086-A | ABSORBER USED IN TRANSPARENT PLASTICS | GENTEX CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |