Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124456 | 0.82 | GABRA1 (0.44) | HSD17B10ALOX15ALOX12GABRA1GABRB1 | |
| SCHEMBL10512706 | 0.76 | NMT1 (0.34) | — | |
| SCHEMBL9419408 | 0.75 | TDP1 (0.36) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL3197724 | 0.75 | HSD17B10 (0.39) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL7121673 | 0.73 | THRA (0.35) | TDP1CYP3A4TSHRALOX15 | |
| SCHEMBL3803700 | 0.69 | TDP1 (0.45) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL27503034 | 0.67 | TSHR (0.43) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL28973883 | 0.65 | TDP1 (0.41) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL301662 | 0.65 | HSD17B10 (0.59) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL6229593 | 0.65 | HSD17B10 (0.39) | TDP1CYP3A4TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | claimed |