Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067066 | 0.73 | TDP1 (0.36) | CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL28036540 | 0.71 | ALOX5 (0.44) | ALOX5PTGS2MEN1TP53CYP3A4 | |
| SCHEMBL6514876 | 0.71 | THRB (0.54) | THRATHRBALOX5MEN1TSHR | |
| SCHEMBL7614059 | 0.71 | ALOX5 (0.53) | ALOX5PTGS2MEN1TP53CYP3A4 | |
| SCHEMBL8400495 | 0.71 | ALOX5 (0.53) | ALOX5PTGS2MEN1TP53CYP3A4 | |
| SCHEMBL8526649 | 0.70 | THRA (0.40) | THRATHRBMEN1HTTKMT2A | |
| SCHEMBL7063016 | 0.69 | ALOX5 (0.39) | THRATHRBALOX5MEN1CYP3A4 | |
| SCHEMBL11398840 | 0.69 | THRA (0.61) | THRATHRBMEN1TSHRKMT2A | |
| SCHEMBL20696027 | 0.69 | THRA (0.61) | THRATHRBMEN1TSHRKMT2A | |
| SCHEMBL20696030 | 0.69 | THRA (0.61) | THRATHRBMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | claimed |