SCHEMBL9067136

SCHEMBL9067136

Cc1cccc(N2C(=O)C=CC2=O)c1N1C(=O)C=CC1=O

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.68
TLR9 Q9NR96 2/20 0.56
FAAH O00519 2/20 0.47
HSP90AA1 P07900 3/20 0.44
ALDH1A1 P00352 3/20 0.40
PKM P14618 2/20 0.40
CCR6 P51684 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 2/20 0.40
ATM Q13315 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
NLRP1 Q9C000 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331778 0.87 MGLL (0.59) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL635306 0.85 TLR9 (0.68) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL29440938 0.82 MGLL (0.70) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL710771 0.82 MGLL (0.70) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL137793 0.81 MGLL (1.00) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL29366282 0.81 MGLL (1.00) MGLLTLR9FAAHHSP90AA1ALDH1A1
Ethane SCHEMBL8584291 0.79 MGLL (0.96) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL144793 0.79 MGLL (0.65) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL9172500 0.78 MGLL (0.66) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL11878725 0.78 MGLL (0.50) MGLLTLR9FAAHHSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0230741-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-08-05 EP claimed
WO-2017108946-A1 THERMOSETTING RESIN COMPOSITIONS HEXCEL COMPOSITES LIMITED (GB) 2017-06-29 WO disclosed
EP-0488389-B1 Prepregs, process for producing the same and laminates produced with the same MITSUBISHI RAYON CO (JP) 1996-10-16 EP disclosed
WO-1995019578-A1 OPTICAL MATERIAL FOR MAKING OPTICAL GUIDES FLAMEL TECHNOLOGIES (FR) 1995-07-20 WO disclosed
US-5279893-A Fiber reinforced composite MITSUBISHI RAYON CO., LTD. (JP) 1994-01-18 US disclosed
EP-0375079-B1 ALKENYLPHOXYLIMIDE MODIFIED POLYIMIDE Technochemie GmbH - Verfahrenstechnik (DE) 1993-06-09 EP disclosed
US-5120824-A Molding materials based on unsaturated monomers containing imide groups; engineering thermoplastics; toughness; heat resistance TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1992-06-09 US disclosed
EP-0488389-A2 Prepregs, process for producing the same and laminates produced with the same MITSUBISHI RAYON CO., LTD. (JP) 1992-06-03 EP disclosed
US-4981934-A Curable composition comprising bis-imide and bis-(alkenyl phenol) TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1991-01-01 US disclosed
EP-0390565-A2 Imide prepolymers, cured products, method for making the same, laminate preparation, and encapsulating compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-10-03 EP disclosed
EP-0375079-A2 Alkenylphoxylimide modified polyimide Technochemie GmbH - Verfahrenstechnik (DE) 1990-06-27 EP disclosed
EP-0355926-A2 Alkenyl-modified polyimides Technochemie GmbH - Verfahrenstechnik (DE) 1990-02-28 EP disclosed
EP-0230741-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-08-05 EP disclosed
EP-0102722-B1 MODIFIED THERMOSETTING IMIDE RESINS The Boots Company PLC (GB) 1986-10-01 EP disclosed
US-4587281-A BISIMIDES CURED WITH POLYISOCYANATES THE BOOTS COMPANY PLC (GB) 1986-05-06 US disclosed
US-4520145-A BISIMIDE, POLYISOCYANATE, AND UNSATURATED POLYESTER THE BOOTS COMPANY PLC (GB) 1985-05-28 US disclosed
EP-0102722-A1 Modified thermosetting imide resins The Boots Company PLC (GB) 1984-03-14 EP disclosed