Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413690 | 0.84 | ALOX5 (0.42) | ALOX5TAAR1NOTUMESR2NPC1 | |
| SCHEMBL4280216 | 0.82 | HSD17B1 (0.44) | ESR2TSHR | |
| SCHEMBL8315352 | 0.82 | ALOX5 (0.41) | ALOX5TAAR1NOTUMESR2NPC1 | |
| SCHEMBL6576709 | 0.80 | CYP2A6 (0.38) | ESR2NPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9648703 | 0.79 | ALOX5 (0.44) | ALOX5TAAR1NOTUMESR2NPC1 | |
| SCHEMBL9649083 | 0.78 | ALOX5 (0.38) | ALOX5TAAR1ESR2TP53IDO1 | |
| SCHEMBL1403761 | 0.77 | CYP2A6 (0.39) | ALOX5TAAR1NPC1TP53TSHR | |
| SCHEMBL9203020 | 0.75 | ALOX5 (0.42) | ALOX5NOTUMESR2NPC1NFKB1 | |
| SCHEMBL7509509 | 0.73 | ALOX5 (0.41) | ALOX5TAAR1NOTUMESR2NPC1 | |
| SCHEMBL4282164 | 0.73 | LMNA (0.45) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571808-A | SUBSTITUTED 2-ARYL-3-AROYLBENZO(B)THIOPHENES | ELI LILLY AND COMPANY (US) | 1996-11-05 | — | — | US | disclosed |