Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.47 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067769 | 1.00 | MAPT (0.70) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL519291 | 0.85 | MAPT (0.72) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL9068415 | 0.84 | SMN1; SMN2 (0.58) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL9068410 | 0.84 | SMN1; SMN2 (0.58) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL20364255 | 0.81 | CA1 (0.50) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL9068343 | 0.81 | CA1 (0.50) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL9068404 | 0.81 | CA1 (0.50) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL5252880 | 0.81 | KYAT1 (0.67) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL6107763 | 0.81 | KYAT1 (0.67) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL5252876 | 0.81 | KYAT1 (0.67) | MAPTSMN1; SMN2GAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506228-A | 2,6-diaryl pyridazinones with immunosuppressant activity | MERCK & CO., INC. (US) | 1996-04-09 | — | — | US | disclosed |