Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067785 | 1.00 | MAPT (0.54) | MAPTALOX12ALDH1A1HPGDMEN1 | |
| SCHEMBL15047097 | 0.86 | MAPT (0.49) | MAPTALOX12ALDH1A1HPGDMEN1 | |
| SCHEMBL8859290 | 0.86 | MAPT (0.49) | MAPTALOX12ALDH1A1HPGDMEN1 | |
| SCHEMBL8588659 | 0.86 | MAPT (0.49) | MAPTALOX12ALDH1A1HPGDMEN1 | |
| SCHEMBL9068425 | 0.85 | MAPT (0.61) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9068423 | 0.85 | MAPT (0.61) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9068037 | 0.82 | MAPT (0.51) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9068034 | 0.82 | MAPT (0.51) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9068185 | 0.81 | LMNA (0.56) | MAPTALOX12ALDH1A1HPGDMEN1 | |
| SCHEMBL9068191 | 0.81 | LMNA (0.56) | MAPTALOX12ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506228-A | 2,6-diaryl pyridazinones with immunosuppressant activity | MERCK & CO., INC. (US) | 1996-04-09 | — | — | US | disclosed |