Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068185 | 1.00 | LMNA (0.56) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL9067641 | 0.93 | LMNA (0.53) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL9068354 | 0.93 | LMNA (0.53) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL8859511 | 0.89 | LMNA (0.52) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL8859265 | 0.89 | LMNA (0.52) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL8590564 | 0.89 | LMNA (0.52) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL8859505 | 0.89 | LMNA (0.52) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL9068423 | 0.88 | MAPT (0.61) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL9068425 | 0.88 | MAPT (0.61) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL8859333 | 0.87 | ALDH1A1 (0.49) | LMNAALDH1A1HPGDTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506228-A | 2,6-diaryl pyridazinones with immunosuppressant activity | MERCK & CO., INC. (US) | 1996-04-09 | — | — | US | disclosed |