Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067905 | 0.88 | TSHR (0.45) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL9066904 | 0.83 | THRB (0.52) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL9067403 | 0.80 | TSHR (0.51) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL9067981 | 0.80 | TSHR (0.56) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL2020675 | 0.80 | TSHR (0.45) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL148579 | 0.76 | TSHR (0.58) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL11810640 | 0.76 | TSHR (0.45) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL9550525 | 0.75 | TSHR (0.48) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL13108239 | 0.74 | TSHR (0.44) | TSHRALDH1A1THRBPOLBAPEX1 | |
| Hydrochloric Acid SCHEMBL14976774 | 0.74 | TSHR (0.56) | TSHRALDH1A1THRBPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537972-B1 | Treating solution for contact lenses | NOF CORP (JP) | 1996-07-10 | — | — | EP | claimed |