SCHEMBL2020675

SCHEMBL2020675

C=C(C)C(=O)OCOP(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 2/20 0.44
THRB P10828 1/20 0.42
BTN3A1 O00481 1/20 0.36
TPI1 P60174 1/20 0.33
LPAR3 Q9UBY5 3/20 0.32
LPAR1 Q92633 2/20 0.32
LPAR2 Q9HBW0 2/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PEPD P12955 1/20 0.31
PGD P52209 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11810640 0.88 TSHR (0.45) TSHRALDH1A1THRBBTN3A1POLB
SCHEMBL13108239 0.86 TSHR (0.44) TSHRALDH1A1THRBBTN3A1POLB
SCHEMBL21051155 0.85 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL17705188 0.83 TSHR (0.45) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL11474626 0.82 TSHR (0.41) TSHRALDH1A1THRBBTN3A1
SCHEMBL29614442 0.82 THRB (0.55) TSHRALDH1A1THRBBTN3A1LPAR3
SCHEMBL41531 0.82 THRB (0.55) TSHRALDH1A1THRBBTN3A1LPAR3
SCHEMBL16715912 0.81 THRB (0.46) TSHRALDH1A1THRBBTN3A1TDP1
SCHEMBL3682160 0.80 TSHR (0.42) TSHRALDH1A1THRBPOLBAPEX1
Ammonia Solution, Strong SCHEMBL18139579 0.80 THRB (0.53) TSHRALDH1A1THRBBTN3A1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114524841-B Multifunctional monomer compound, preparation method thereof and photosensitive resin composition 固安鼎材科技有限公司 2024-02-23 CN claimed
EP-3087128-B1 FLAME-RETARDANT COPOLYMERS OF DIALKYL (METH)ACRYLOYLOXYALKYL PHOSPHATE OR DIALKYL (METH)ACRYLOYLOXYALKYL PHOSPHONATE MONOMERS AND POLYMER FOAMS BASED MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-11 EP claimed
CN-104262528-A Preparation method for flame-retardant acrylic rubber SHANGHAI HUAYI GROUP CO 2015-01-07 CN claimed
EP-0509516-B1 Dental restoration composition SANKIN IND CO (JP) 1997-03-26 EP claimed
EP-0509516-A2 Dental restoration composition SANKIN KOGYO KABUSHIKI KAISHA (JP) 1992-10-21 EP claimed
US-12178938-B2 UV absorbing ocular lens SEED CO., LTD. (JP) 2024-12-31 US disclosed
EP-3894909-B1 UV ABSORBING OCULAR LENS SEED CO LTD (JP) 2024-07-31 EP disclosed
CN-113316727-B UV absorbing ophthalmic lenses 株式会社实瞳 2024-07-09 CN disclosed
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT SHOFU INC. (JP) 2024-05-30 US disclosed
CN-114524841-B Multifunctional monomer compound, preparation method thereof and photosensitive resin composition 固安鼎材科技有限公司 2024-02-23 CN disclosed
EP-4321145-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT Shofu Inc. (JP) 2024-02-14 EP disclosed
US-11735737-B2 Binder for electricity storage devices improving dispersibility of conductive assistant FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2023-08-22 US disclosed
US-6455476-B1 Composition and process for lubricated plastic working of metals HENKEL CORPORATION 2002-09-24 US disclosed
US-6447620-B1 Water-based surface-treating agent for metallic material HENKEL CORPORATION 2002-09-10 US disclosed
EP-1093510-A4 COMPOSITION AND PROCESS FOR LUBRICATED PLASTIC WORKING OF METALS HENKEL CORP (US) 2002-06-05 EP disclosed
EP-1093510-A1 COMPOSITION AND PROCESS FOR LUBRICATED PLASTIC WORKING OF METALS HENKEL CORPORATION (US) 2001-04-25 EP disclosed
WO-1999064544-A1 COMPOSITION AND PROCESS FOR LUBRICATED PLASTIC WORKING OF METALS HENKEL CORPORATION (US) 1999-12-16 WO disclosed
EP-0509516-B1 Dental restoration composition SANKIN IND CO (JP) 1997-03-26 EP disclosed
US-5306338-A Powder of fluoride-releasing glass filler, accelerator to be mixed with liquid of dimethacrylate monomers, water soluble methacryloxyalkyl phosphate, photoinitiator, diluent SANKIN KOGYO K.K. (JP) 1994-04-26 US disclosed
EP-0509516-A2 Dental restoration composition SANKIN KOGYO KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT GRIK1, GRIN2B, GRIK2 TSHR 2655/4885ALDH1A1 1560/4885THRB 599/4885
US-12178938-B2 UV absorbing ocular lens UACA, PHYKPL, UROD TSHR 3486/4885ALDH1A1 592/4885THRB 4337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.