Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SAT1 | P21673 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810640 | 0.86 | TSHR (0.45) | TSHRALDH1A1THRBBTN3A1POLB | |
| SCHEMBL17705188 | 0.86 | TSHR (0.45) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL2020675 | 0.86 | TSHR (0.45) | TSHRALDH1A1THRBBTN3A1POLB | |
| SCHEMBL21051155 | 0.83 | TSHR (0.47) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL10018234 | 0.82 | THRB (0.53) | TSHRALDH1A1THRBBTN3A1POLB | |
| SCHEMBL11474626 | 0.81 | TSHR (0.41) | TSHRALDH1A1THRBBTN3A1 | |
| SCHEMBL14444211 | 0.79 | TSHR (0.58) | TSHRALDH1A1THRBBTN3A1POLB | |
| SCHEMBL17676125 | 0.79 | TSHR (0.53) | TSHRALDH1A1THRBBTN3A1POLB | |
| SCHEMBL16715912 | 0.79 | THRB (0.46) | TSHRALDH1A1THRBBTN3A1TDP1 | |
| SCHEMBL14019302 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1BTN3A1SAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140161901-A1 | DENTAL COMPOSITION | ZIMMER DENTAL, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-7811601-B2 | Naphazoline nitrate; hydrophilic; copolymer of hydroxyalkyl acrylate, alkylphosphate ester of methacrylic acid, methacrylamide; ionic gel | SEED CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140161901-A1 | DENTAL COMPOSITION | CAD, PPIP5K2, PTH1R | TSHR 3937/4885ALDH1A1 3775/4885THRB 1732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.