Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128290 | 0.90 | AR (0.49) | AXLARADORA3HSD11B1AKR1C3 | |
| SCHEMBL2465443 | 0.82 | RECQL (0.49) | AXLARCYP3A4MAOAMAOB | |
| SCHEMBL11251216 | 0.78 | GSK3B (0.44) | ANPEPCYP3A4ALDH1A1MAPTALOX15 | |
| SCHEMBL8093303 | 0.78 | ANPEP (0.41) | ANPEPMAOAMAOBMEN1USP2 | |
| SCHEMBL5082125 | 0.76 | AR (0.53) | ARADORA3HSD11B1AKR1C3CYP3A4 | |
| SCHEMBL2283832 | 0.75 | CYP3A4 (0.49) | ARADORA3CYP3A4MAOAMAOB | |
| SCHEMBL8093208 | 0.74 | ALDH1A1 (0.48) | ANPEPMEN1USP2ALDH1A1MAPT | |
| SCHEMBL6575792 | 0.74 | ALOX5 (0.44) | CYP3A4MEN1ALDH1A1ALOX5MAPT | |
| SCHEMBL5088610 | 0.74 | CYP19A1 (0.47) | ARADORA3CYP3A4MAOAMAOB | |
| SCHEMBL21518315 | 0.74 | CYP19A1 (0.39) | ARADORA3CYP3A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040086983-A1 | Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase | MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) | 2004-05-06 | — | — | US | claimed |
| US-20040086983-A1 | Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase | MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |