Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL30111933 | 0.93 | CES1 (0.36) | KIF11CES1CYP2C19KCNN4CYP2D6 | |
| SCHEMBL5069848 | 0.79 | KIF11 (0.38) | KIF11CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL5483343 | 0.77 | CES1 (0.37) | CES1ALDH1A1CYP2C19KCNN4CYP2D6 | |
| SCHEMBL8906872 | 0.71 | NR1H2 (0.32) | CHRM3MEN1KMT2A | |
| SCHEMBL2205526 | 0.71 | NR1H2 (0.32) | CHRM3MEN1KMT2A | |
| SCHEMBL10591561 | 0.68 | ESR2 (0.36) | KIF11ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5133753 | 0.68 | CES1 (0.44) | CES1ALDH1A1CYP2C19KCNN4KMT2A | |
| SCHEMBL6855004 | 0.67 | CES1 (0.40) | KIF11CES1ALDH1A1CYP2C19KCNN4 | |
| SCHEMBL3205214 | 0.63 | KCNN4 (0.41) | KIF11CES1ALDH1A1CYP2C19KCNN4 | |
| SCHEMBL6671847 | 0.63 | CYP2C19 (0.42) | ALDH1A1CYP2C19CYP2D6HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427458-A | Transglutaminase mediated conjugation | 塔拉克治疗公司 | 2022-12-02 | — | — | CN | disclosed |
| WO-1996034008-A1 | NOVEL ANTISENSE NUCLEIC ACIDS DIRECTED AGAINST RAS ONCOGENES, THEIR PREPARATION AND USE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1996-10-31 | — | — | WO | disclosed |