Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | EDNRB | P24530 | 3/20 | 0.31 |
| ▸ | EDNRA | P25101 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068006 | 0.77 | KIF11 (0.35) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL10512565 | 0.75 | CES1 (0.40) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL10417502 | 0.74 | KCNN4 (0.47) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL5133753 | 0.71 | CES1 (0.44) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL5069848 | 0.71 | KIF11 (0.38) | CYP2D6CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL4372562 | 0.66 | CES1 (0.47) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL28117527 | 0.66 | CES1 (0.47) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL319709 | 0.66 | CES1 (0.47) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL20357349 | 0.66 | ALDH1A1 (0.46) | CES1KCNN4ALDH1A1ALOX15MAPK1 | |
| SCHEMBL20702253 | 0.66 | ALDH1A1 (0.46) | CES1KCNN4ALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117773-A1 | Telomerase-inhibiting ENA oligonucleotide | SANKYO COMPANY, LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
| EP-1783216-A1 | TELOMERASE-INHIBITORY ENA OLIGONUCLEOTIDE | Sankyo Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117773-A1 | Telomerase-inhibiting ENA oligonucleotide | TERT, ENO1, TERB1 | CES1 3999/4885KCNN4 3006/4885ALDH1A1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.