Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | EPOR | P19235 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068006 | 0.79 | KIF11 (0.35) | KIF11CYP2D6CYP2C9CYP2C19 | |
| Glycolic Acid SCHEMBL30111933 | 0.73 | CES1 (0.36) | KIF11CYP2D6CYP2C19 | |
| SCHEMBL10591561 | 0.71 | ESR2 (0.36) | KIF11CYP3A4 | |
| SCHEMBL5483343 | 0.71 | CES1 (0.37) | CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10586389 | 0.66 | KIF11 (0.41) | KIF11KCNH2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27462507 | 0.64 | LTB4R (0.37) | CYP3A4CYP2D6 | |
| SCHEMBL5023008 | 0.63 | KIF11 (0.56) | KIF11KCNH2SLC7A5 | |
| SCHEMBL16473050 | 0.63 | CPB2 (0.37) | — | |
| SCHEMBL7145599 | 0.62 | KIF11 (0.38) | KIF11KCNH2 | |
| SCHEMBL5133753 | 0.62 | CES1 (0.44) | CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991552-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | Epoch Biosciences, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007098182-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| EP-1781675-A2 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | Epoch Biosciences, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006020947-A2 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2006-02-23 | — | — | WO | disclosed |