Urea

Urea

SCHEMBL9068018

CCO[SiH](OCC)OCC.NC(N)=O.NC(N)=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.46
ALDH1A1 P00352 4/20 0.36
LMNA P02545 3/20 0.35
OR51E2 Q9H255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
PARP10 Q53GL7 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
CYP1A2 P05177 1/20 0.31
TRPA1 O75762 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL9068285 1.00 ALOX15 (0.46) ALOX15ALDH1A1LMNAOR51E2TDP1
Urea SCHEMBL11669587 0.92 ALOX15 (0.40) ALOX15ALDH1A1LMNAOR51E2TDP1
Carbamic Acid SCHEMBL20814677 0.92 ALOX15 (0.43) ALOX15ALDH1A1LMNAHSD17B10MGAM
Acetone SCHEMBL28132690 0.85 ALDH1A1 (0.43) ALOX15ALDH1A1LMNATDP1HSD17B10
Urethane SCHEMBL9751342 0.85 ALOX15 (0.71) ALOX15ALDH1A1LMNAHSD17B10MGAM
Acetic Acid SCHEMBL2248274 0.82 FFAR3 (0.41) ALOX15ALDH1A1LMNATDP1HSD17B10
Thiourea SCHEMBL12614271 0.82 TSHR (0.35) ALOX15TSHR
SCHEMBL28485327 0.81 ALOX15 (0.36) ALOX15LMNAHSD17B10PARP10
Methylamine SCHEMBL978488 0.81
Methyl Alcohol SCHEMBL27815477 0.81 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0625176-B1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS MINNESOTA MINING & MFG (US) 1996-12-04 EP disclosed
EP-0625176-A1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS. MINNESOTA MINING & MFG (US) 1994-11-23 EP disclosed
US-5286815-A Containing an acid catalyst MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-02-15 US disclosed
WO-1993016142-A1 MOISTURE CURABLE POLYSILOXANE RELEASE COATING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-19 WO disclosed