Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032150 | 0.86 | LMNA (0.49) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL9030000 | 0.84 | MAPT (0.47) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL377354 | 0.83 | MAPT (0.46) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL9029961 | 0.83 | KMT2A (0.48) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL9246536 | 0.83 | MAPT (0.46) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL29456982 | 0.83 | MAPT (0.46) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL8789647 | 0.79 | MAPT (0.50) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL9016031 | 0.74 | MAPT (0.50) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL8830260 | 0.71 | SGMS2 (0.52) | MAPTL3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL8830256 | 0.70 | TSHR (0.43) | MAPTL3MBTL1MAPK1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556886-A | VIRICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-09-17 | — | — | US | disclosed |