Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948521 | 0.84 | CYP1A2 (0.49) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL30451723 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL27781696 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL11201638 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL29653751 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL20548070 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL27545476 | 0.82 | L3MBTL1 (0.46) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL8543190 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL2678980 | 0.81 | L3MBTL1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL15346268 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4ERAB9ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521871-A4 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | — | 1993-03-10 | — | — | EP | claimed |
| EP-0521871-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1993-01-13 | — | — | EP | claimed |
| WO-1991011988-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1991-08-22 | — | — | WO | claimed |
| US-5495044-A | Inhibitors of kynureninase | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1995011878-A1 | INHIBITORS OF KYNURENINASE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-05-04 | — | — | WO | disclosed |
| EP-0581907-A4 | — | — | 1994-04-06 | — | — | EP | disclosed |
| EP-0581907-A1 | INHIBITORS OF KYNURENINASE | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| EP-0521871-A4 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0521871-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1992018003-A1 | INHIBITORS OF KYNURENINASE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| WO-1991011988-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1991-08-22 | — | — | WO | disclosed |