Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653846 | 0.90 | GPR35 (0.39) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL27545476 | 0.85 | L3MBTL1 (0.46) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL2678980 | 0.84 | L3MBTL1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL9068341 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL11778207 | 0.83 | L3MBTL1 (0.45) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL7948521 | 0.82 | CYP1A2 (0.49) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL29653751 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL30451723 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL27781696 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4ERAB9ANPC1RECQL | |
| SCHEMBL8543190 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4ERAB9ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016611-B1 | TRIPEPTIDES, PROCESS FOR THEIR PREPARATION, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND METHODS FOR THEIR USE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-08-17 | — | — | EP | claimed |
| EP-0016611-A2 | Tripeptides, process for their preparation, therapeutic compositions containing them and methods for their use | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-10-01 | — | — | EP | claimed |