Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068743 | 0.84 | GABRA1 (0.43) | CA2CYP3A4FAAHCA1LMNA | |
| SCHEMBL8395122 | 0.84 | CA2 (0.43) | CA2GABRA1TSHRGABRB2ALDH1A1 | |
| SCHEMBL7635494 | 0.80 | CA2 (0.40) | CA2CYP3A4FAAHCA1LMNA | |
| SCHEMBL14560669 | 0.79 | CA2 (0.39) | CA2CYP3A4FAAHCA1LMNA | |
| SCHEMBL49976 | 0.77 | GABRA1 (0.42) | CA2CYP3A4FAAHCA1LMNA | |
| SCHEMBL9068401 | 0.74 | SCN5A (0.39) | TSHRALDH1A1 | |
| SCHEMBL9068223 | 0.73 | KDM4E (0.38) | CYP3A4LMNASLC6A2HTR2CHTR2B | |
| SCHEMBL20696113 | 0.73 | GABRA1 (0.40) | CA2CYP3A4FAAHCA1LMNA | |
| SCHEMBL10343213 | 0.72 | CA2 (0.48) | CA2CYP1A2GABRA1TSHRGABRB2 | |
| SCHEMBL13408064 | 0.72 | ALDH1A1 (0.40) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521237-A | HEAT, OXIDATION, AND RADIATION RESISTANT POLYOLEFINS FOR PROTECTIVE COATINGS THAT RESIST DISCOLORATION | CIBA-GEIGY CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |