Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MME | P08473 | 3/20 | 0.56 |
| ▸ | ACE | P12821 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068565 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MMEACEMEN1LMNA | |
| SCHEMBL23835494 | 0.86 | ACE (0.71) | ACEMAPT | |
| SCHEMBL15223612 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL930664 | 0.86 | ACE (0.71) | ACEMAPT | |
| SCHEMBL2871612 | 0.85 | MME (0.68) | ALDH1A1MMEACEMEN1LMNA | |
| SCHEMBL9067110 | 0.84 | MME (0.67) | ALDH1A1MMEACEMEN1LMNA | |
| SCHEMBL9068520 | 0.83 | ACE (0.56) | MMEACE | |
| SCHEMBL9545240 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MMEACEMEN1LMNA | |
| SCHEMBL9545245 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MMEACEMEN1LMNA | |
| SCHEMBL929013 | 0.81 | ACE (0.55) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |