Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512808 | 0.80 | APEX1 (0.36) | ALDH1A1HSD11B1ADORA3LMNA | |
| SCHEMBL206785 | 0.75 | MEN1 (0.49) | MEN1KMT2AALDH1A1L3MBTL1PKM | |
| SCHEMBL4500488 | 0.74 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2L3MBTL1PKM | |
| SCHEMBL4518124 | 0.73 | MEN1 (0.42) | MEN1KMT2AGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL1896319 | 0.71 | MEN1 (0.40) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL9068592 | 0.62 | APEX1 (0.36) | GAAAKR1C3 | |
| SCHEMBL9068590 | 0.60 | L3MBTL1 (0.36) | MEN1KMT2AL3MBTL1CHRNB2CHRNB4 | |
| SCHEMBL6639799 | 0.60 | HSD11B1 (0.35) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL31655180 | 0.59 | KMT2A (0.38) | MEN1KMT2AALDH1A1CYP2C9CHRNB2 | |
| SCHEMBL26623315 | 0.59 | NOTUM (0.33) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188299-B2 | Acrylate derivatives, alcohol derivatives, and method for producing them | KURARAY CO., LTD. (JP) | 2012-05-29 | — | — | US | disclosed |