Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965298 | 0.81 | ALOX5 (0.60) | ALOX5HDAC6CYSLTR2CYSLTR1 | |
| SCHEMBL8800737 | 0.81 | ALOX5 (0.51) | ALOX5HDAC6 | |
| SCHEMBL8801377 | 0.80 | ALOX5 (0.50) | ALOX5HDAC6 | |
| SCHEMBL8800310 | 0.77 | ALOX5 (0.82) | ALOX5HDAC6 | |
| SCHEMBL8800827 | 0.77 | ALOX5 (0.82) | ALOX5HDAC6 | |
| SCHEMBL3519488 | 0.77 | GPBAR1 (0.68) | ALOX5HDAC6CYSLTR2CYSLTR1 | |
| SCHEMBL8800840 | 0.77 | FFAR1 (0.61) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL7592907 | 0.76 | GPBAR1 (0.67) | ALOX5HDAC6CYSLTR2CYSLTR1 | |
| SCHEMBL7592890 | 0.76 | GPBAR1 (0.67) | ALOX5HDAC6CYSLTR2CYSLTR1 | |
| SCHEMBL2109295 | 0.76 | ALOX5 (1.00) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | claimed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | claimed |