Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965945 | 0.90 | ALOX5 (0.54) | ALOX5HDAC6 | |
| SCHEMBL9068707 | 0.81 | ALOX5 (0.61) | ALOX5HDAC6CYSLTR2CYSLTR1 | |
| SCHEMBL8965352 | 0.81 | ALOX5 (0.51) | ALOX5HDAC6FFAR1 | |
| SCHEMBL8965327 | 0.80 | ALOX5 (0.49) | ALOX5HDAC6FFAR1 | |
| SCHEMBL8965904 | 0.78 | FFAR1 (0.63) | ALOX5CYSLTR2CYSLTR1FFAR1AKR1B1 | |
| SCHEMBL7818344 | 0.75 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9030094 | 0.75 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL2109295 | 0.75 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL7818529 | 0.75 | ALOX5 (1.00) | ALOX5HDAC6 | |
| SCHEMBL9123409 | 0.75 | ALOX5 (1.00) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |