Sebacic Acid

Sebacic Acid

SCHEMBL9068801

C=C(CC(=O)O)C(=O)O.O=C(O)CCCCCCCCC(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.58
HSD17B10 Q99714 2/20 0.58
TSHR P16473 5/20 0.57
LMNA P02545 3/20 0.57
NFKB1 P19838 1/20 0.57
PMP22 Q01453 1/20 0.57
GPR84 Q9NQS5 6/20 0.48
FFAR1 O14842 2/20 0.48
FFAR4 Q5NUL3 2/20 0.48
ABCC4 O15439 1/20 0.46
MAPT P10636 1/20 0.46
PRMT1 Q99873 1/20 0.46
PPARG P37231 6/20 0.46
PPARD Q03181 6/20 0.46
PPARA Q07869 6/20 0.46
HDAC11 Q96DB2 5/20 0.46
ALDH1A1 P00352 3/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MEN1 O00255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL6835410 0.98 ALOX15 (0.60) ALOX15HSD17B10TSHRLMNANFKB1
Adipic Acid SCHEMBL8897172 0.91 ALOX15 (0.54) ALOX15HSD17B10TSHRLMNANFKB1
Stearic Acid SCHEMBL29145471 0.90 GPR84 (0.65) ALOX15HSD17B10TSHRLMNAGPR84
Itaconate SCHEMBL16880252 0.87 ALOX15 (0.65) ALOX15HSD17B10TSHRLMNANFKB1
Itaconate SCHEMBL17006690 0.87
SCHEMBL2994334 0.85 TSHR (0.63) ALOX15HSD17B10TSHRLMNANFKB1
SCHEMBL699958 0.85 TSHR (0.63) ALOX15HSD17B10TSHRLMNANFKB1
SCHEMBL3505291 0.85 TSHR (0.63) ALOX15HSD17B10TSHRLMNANFKB1
SCHEMBL156052 0.85 TSHR (0.63) ALOX15HSD17B10TSHRLMNANFKB1
Itaconate SCHEMBL3579855 0.85 ALOX15 (0.52) ALOX15HSD17B10TSHRLMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502332-A Composite material comprising synthetic filler and specific polymer UNIV AMSTERDAM 2014-01-08 CN disclosed
CN-103502371-A Laminate comprising a carrier and a coating layer UNIV AMSTERDAM 2014-01-08 CN disclosed
CN-103502331-A Composite material comprising bio-filler and specific polymer UNIV AMSTERDAM 2014-01-08 CN disclosed
US-5559189-A Fast curing thermosetting acetylenic polymeric vehicle EASTER MICHIGAN UNIVERSITY (US) 1996-09-24 US disclosed