Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.54 |
| ▸ | ACE | P12821 | 4/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068556 | 0.99 | MME (0.53) | MMEACE | |
| SCHEMBL9068533 | 0.87 | MME (0.62) | MMEACE | |
| SCHEMBL7446860 | 0.86 | HDAC1 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7446865 | 0.86 | HDAC1 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7304584 | 0.81 | MME (0.46) | MMEACE | |
| SCHEMBL9069257 | 0.81 | MME (0.62) | MMEACEITGB3ITGA2B | |
| SCHEMBL8837469 | 0.80 | FCER2 (0.50) | MMEACE | |
| SCHEMBL9068708 | 0.80 | MME (0.73) | MMEACE | |
| SCHEMBL9069167 | 0.80 | MME (0.60) | MMEACE | |
| SCHEMBL7450894 | 0.80 | MME (0.52) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0161769-B1 | ENKEPHALINASE INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1987-10-28 | — | — | EP | disclosed |
| EP-0161769-A1 | Enkephalinase inhibitors | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |