Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.62 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068906 | 0.87 | MME (0.54) | MMEACE | |
| SCHEMBL9068556 | 0.85 | MME (0.53) | MMEACE | |
| SCHEMBL8837469 | 0.84 | FCER2 (0.50) | MMEACEPAMCYP3A4MAPK1 | |
| SCHEMBL7450894 | 0.84 | MME (0.52) | MMEACEPAMCYP3A4MAPK1 | |
| SCHEMBL9587602 | 0.83 | MME (0.48) | MMEACEPAMCYP3A4MAPK1 | |
| SCHEMBL7298881 | 0.82 | MME (0.58) | MMEACEPAMCYP3A4MAPK1 | |
| SCHEMBL9587952 | 0.82 | MME (0.47) | MMEACEPAMCYP3A4MAPK1 | |
| SCHEMBL7304584 | 0.80 | MME (0.46) | MMEACECYP3A4 | |
| SCHEMBL9588793 | 0.80 | CYP3A4 (0.46) | MMEACEPAMCYP3A4MAPK1 | |
| SCHEMBL18576675 | 0.80 | CTRB1 (0.65) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |