Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23623799 | 0.84 | NPC1 (0.54) | NPC1RAB9AHDAC3NCOR2CASP1 | |
| SCHEMBL12304173 | 0.82 | NPC1 (0.56) | NPC1RAB9AHDAC3NCOR2MMP2 | |
| SCHEMBL38657612 | 0.81 | NPC1 (0.51) | NPC1RAB9AHDAC3NCOR2MMP2 | |
| SCHEMBL7395723 | 0.80 | NPC1 (0.50) | NPC1RAB9AHDAC3NCOR2MMP2 | |
| SCHEMBL9068949 | 0.78 | NPC1 (0.48) | NPC1RAB9AHDAC3NCOR2MMP2 | |
| SCHEMBL7416043 | 0.76 | NPC1 (0.51) | NPC1RAB9AHDAC3NCOR2MMP2 | |
| SCHEMBL11911576 | 0.75 | NPC1 (0.51) | NPC1RAB9AHDAC3NCOR2CASP1 | |
| SCHEMBL7424713 | 0.75 | NPC1 (0.62) | NPC1RAB9AHDAC3NCOR2CASP1 | |
| SCHEMBL906398 | 0.75 | RAB9A (0.62) | NPC1RAB9AHDAC3NCOR2 | |
| SCHEMBL7380368 | 0.75 | NPC1 (0.48) | NPC1RAB9AHDAC3NCOR2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |