SCHEMBL9069999

SCHEMBL9069999

O=C(F)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.70
CES1 P23141 2/20 0.70
SRD5A2 P31213 2/20 0.59
GSK3B P49841 2/20 0.57
PTPN1 P18031 2/20 0.57
NR4A1 P22736 1/20 0.52
NR4A2 P43354 1/20 0.52
NR4A3 Q92570 1/20 0.52
MEN1 O00255 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
KMT2A Q03164 1/20 0.50
EPHX2 P34913 1/20 0.50
TRPV1 Q8NER1 2/20 0.48
PTGS1 P23219 2/20 0.48
MMP1 P03956 1/20 0.48
CYP1A1 P04798 1/20 0.47
MAOB P27338 1/20 0.47
CYP1B1 Q16678 1/20 0.47
RORC P51449 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethylbenzene SCHEMBL21291903 0.82 ALDH1A1 (0.58) CES2CES1SRD5A2MEN1TSHR
SCHEMBL3172262 0.82 CES2 (1.00) CES2CES1SRD5A2GSK3BPTPN1
SCHEMBL648641 0.82 SRD5A2 (0.83) CES2CES1SRD5A2GSK3BPTPN1
SCHEMBL10894828 0.81 CES2 (0.46) CES2CES1SRD5A2GSK3BPTPN1
SCHEMBL10702196 0.81 CES2 (0.46) CES2CES1SRD5A2GSK3BPTPN1
SCHEMBL102601 0.81 TSHR (0.47) CES2CES1SRD5A2HPGDTSHR
SCHEMBL349343 0.80 CES2 (0.70) CES2CES1SRD5A2GSK3BPTPN1
SCHEMBL78879 0.80 SRD5A2 (0.87) CES2CES1SRD5A2GSK3BPTPN1
SCHEMBL1330891 0.80 SRD5A2 (0.87) CES2CES1SRD5A2GSK3BPTPN1
SCHEMBL2195841 0.80 CES2 (0.70) CES2CES1SRD5A2GSK3BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115717009-B Perovskite ink and preparation method and application thereof 江苏集萃有机光电技术研究所有限公司 2023-11-14 CN claimed
CN-115717009-A Perovskite ink and preparation method and application thereof 江苏集萃有机光电技术研究所有限公司 2023-02-28 CN claimed
EP-0251041-B1 PROCESS FOR PREPARING 2,3,5,6-TETRAFLUOROBENZOIC ACID AND THE COMPOUNDS 2,3,5,6-TETRACHLORO-4-TRIFLUOROMETHYLBENZOYL CHLORIDE AND 2,3,5,6-TETRAFLUORO-4-TRIFLUOROMETHYLBENZOYL FLUORIDE BAYER AG (DE) 1989-11-08 EP claimed
US-4755621-A Process for the preparation of 2,3,5,6-tetrafluorobenzoic acid, and the new compounds 2,3,5,6-tetrachloro-4-trifluoromethyl-benzoyl chloride and 2,3,5,6-tetrafluoro-4-trifluoromethyl-benzoyl fluoride BAYER AKTIENGESELLSCHAFT (DE) 1988-07-05 US claimed
EP-0251041-A1 Process for preparing 2,3,5,6-tetrafluorobenzoic acid and the compounds 2,3,5,6-tetrachloro-4-trifluoromethylbenzoyl chloride and 2,3,5,6-tetrafluoro-4-trifluoromethylbenzoyl fluoride BAYER AG (DE) 1988-01-07 EP claimed
US-4581179-A Process for the preparation of trifluoromethylbenzoyl chlorides and bromides from trifluoromethylbenzoyl fluorides OCCIDENTAL CHEMICAL CORPORATION (US) 1986-04-08 US claimed
EP-0038223-A1 Process for the preparation of trifluoromethylbenzoyl halides OCCIDENTAL CHEMICAL CORPORATION (US) 1981-10-21 EP claimed
JP-8225491-A None JP disclosed
CN-115259996-B Synthesis method of 2,3,5, 6-tetrafluorobenzyl alcohol 浙江中欣氟材股份有限公司 2024-02-02 CN disclosed
CN-115717009-B Perovskite ink and preparation method and application thereof 江苏集萃有机光电技术研究所有限公司 2023-11-14 CN disclosed
CN-115717009-A Perovskite ink and preparation method and application thereof 江苏集萃有机光电技术研究所有限公司 2023-02-28 CN disclosed
CN-115259996-A Synthetic method of transfluthrin intermediate 浙江中欣氟材股份有限公司 2022-11-01 CN disclosed
CN-113292399-B Synthetic method of transfluthrin intermediate 浙江中欣氟材股份有限公司 2021-11-26 CN disclosed
EP-0038223-B1 PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLBENZOYL HALIDES OCCIDENTAL CHEMICAL CORPORATION (US) 1984-08-08 EP disclosed
US-4454350-A Process for the acylation of halo- or trihalomethylbenzenes RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1984-06-12 US disclosed
US-4446078-A REACTING A POLYHALOALKOXY- OR POLYHALOALKYLTHIOBENZENE WITH A CARBOXYLIC DERIVATIVE, BORON TRIFLUORIDE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-05-01 US disclosed
EP-0038987-B1 PROCESS FOR PREPARING ACYL CYANIDES BAYER AG (DE) 1983-06-08 EP disclosed
EP-0038987-A1 Process for preparing acyl cyanides BAYER AG (DE) 1981-11-04 EP disclosed
EP-0038223-A1 Process for the preparation of trifluoromethylbenzoyl halides OCCIDENTAL CHEMICAL CORPORATION (US) 1981-10-21 EP disclosed
US-4283344-A Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran NIHON NOHYAKU CO., LTD. (JP) 1981-08-11 US disclosed