Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683175 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1NR3C1NR3C2PGR | |
| SCHEMBL14887942 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1NR3C1NR3C2PGR | |
| SCHEMBL17448774 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1NR3C1NR3C2PGR | |
| SCHEMBL14443335 | 0.76 | CRHR1 (0.33) | ALDH1A1 | |
| SCHEMBL30618212 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1PYCR1MEN1USP2 | |
| SCHEMBL8516081 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1PYCR1MEN1USP2 | |
| SCHEMBL15012476 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1PYCR1MEN1USP2 | |
| SCHEMBL14196444 | 0.74 | ALDH1A1 (0.37) | KDM4EALDH1A1NR3C1NR3C2PGR | |
| SCHEMBL9070613 | 0.73 | AGXT (0.48) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3432857 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731791-A1 | NOVEL BENZENESULFONYLIMINE DERIVATIVES AS INHIBITORS OF IL-1 ACTION | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0268878-B1 | Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS (JP) | 1996-01-31 | — | — | EP | disclosed |
| WO-1995014669-A1 | NOVEL BENZENESULFONYLIMINE DERIVATIVES AS INHIBITORS OF IL-1 ACTION | MERRELL PHARMACEUTICALS INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| CN-1016432-B | Salicylic acid copolymer and method for preparing metal salt thereof | MITSUI TOATSU CHEMICAIS INC (JP) | 1992-04-29 | — | — | CN | disclosed |
| US-5023366-A | Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-06-11 | — | — | US | disclosed |
| CN-1051368-A | Salicylic acid copolymers and its metal-salt and preparation method thereof contain the developer of this metal salts of copolymers and the colour developing paper of this developer of employing | MITSUI TOATSU CHEMICALS (JP) | 1991-05-15 | — | — | CN | disclosed |
| CN-87107802-A | Salicylic acid copolymer and metal salt thereof, process for producing the same, color-developing agent containing the copolymer metal salt, and color-developing paper using the color-developing agent | — | 1988-08-10 | — | — | CN | disclosed |
| EP-0268878-A2 | Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-06-01 | — | — | EP | disclosed |