Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417432 | 0.82 | CHKA (0.32) | CHKASMN1; SMN2USP2TDP1HPGD | |
| SCHEMBL7710235 | 0.77 | KDM4E (0.44) | SMN1; SMN2USP2 | |
| SCHEMBL17065181 | 0.63 | — | — | |
| SCHEMBL28059174 | 0.62 | DYRK3 (0.30) | — | |
| SCHEMBL17065184 | 0.60 | — | — | |
| SCHEMBL28059175 | 0.59 | — | — | |
| SCHEMBL14675777 | 0.59 | POLB (0.32) | HPGD | |
| SCHEMBL26599287 | 0.59 | CHRNB2 (0.35) | CHKASMN1; SMN2USP2TDP1HPGD | |
| SCHEMBL1408936 | 0.57 | HPGD (0.35) | CHKASMN1; SMN2USP2TDP1HPGD | |
| SCHEMBL13460691 | 0.57 | USP2 (0.45) | CHKASMN1; SMN2USP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714396-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005383-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-02-23 | — | — | WO | disclosed |