SCHEMBL9070541

SCHEMBL9070541

CCCCCCCCCCCCC(CCOCCC(CCCCCCCCCCCC)CC(O)=S)CC(O)=S

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
GPR84 Q9NQS5 7/20 0.38
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
FFAR1 O14842 1/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
LCK P06239 1/20 0.35
PPARD Q03181 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
SMPD1 P17405 2/20 0.33
FFAR4 Q5NUL3 1/20 0.33
USP2 O75604 1/20 0.33
ACE2 Q9BYF1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755395 0.98 LMNA (0.42) LMNAGPR84MAPTMEN1THRB
SCHEMBL9073883 0.98 LMNA (0.42) LMNAGPR84MAPTMEN1THRB
SCHEMBL7754014 0.93 LMNA (0.37) LMNAGPR84MAPTMEN1THRB
SCHEMBL7755407 0.92 LMNA (0.36) LMNAGPR84MAPTMEN1THRB
SCHEMBL7755423 0.92 ALDH1A1 (0.40) LMNAGPR84CA2
SCHEMBL7754864 0.92 LMNA (0.36) LMNAGPR84MAPTMEN1THRB
SCHEMBL7758079 0.90 LMNA (0.39) LMNAGPR84MAPTMEN1THRB
SCHEMBL7754809 0.90 ALDH1A1 (0.39) LMNAGPR84MAPTMEN1THRB
SCHEMBL7754815 0.90 ALDH1A1 (0.39) LMNAGPR84MAPTMEN1THRB
SCHEMBL7752021 0.90 ALDH1A1 (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4301296-A FOR BUTADIENE-STYRENE COPOLYMER AND ACRYLONITRILE-BUTADIENE COPOLYMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-11-17 US claimed
EP-0470041-B1 Process for the preparation of a rubber having polymer bound functionality GOODYEAR TIRE & RUBBER (US) 1996-02-28 EP disclosed
US-5093517-A Catalyzed ester interchange THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-03 US disclosed
EP-0470041-A1 Process for the preparation of a rubber having polymer bound functionality THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-02-05 EP disclosed
US-5073592-A Oxidation resistant THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-12-17 US disclosed
EP-0282435-B1 IMPROVED METHOD FOR THE ESTERIFICATION OF THIOPROPIONATES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-10-16 EP disclosed
EP-0282435-A1 Improved method for the esterification of thiopropionates THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-09-14 EP disclosed