SCHEMBL9070545

SCHEMBL9070545

CCCCCCCCCCCCC(CCC(CCCCCCCCCCCC)CC(O)=S)CC(O)=S

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
GPR84 Q9NQS5 7/20 0.44
FFAR1 O14842 2/20 0.42
MAPT P10636 1/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
SMPD1 P17405 3/20 0.38
FFAR4 Q5NUL3 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
FDPS P14324 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9074800 0.98 LMNA (0.54) LMNAGPR84FFAR1MAPTLCK
SCHEMBL11440726 0.98 LMNA (0.54) LMNAGPR84FFAR1MAPTLCK
SCHEMBL7752149 0.96 LMNA (0.48) LMNAGPR84FFAR1MAPTLCK
SCHEMBL7752033 0.94 LMNA (0.45) LMNAGPR84FFAR1MAPTLCK
SCHEMBL7752017 0.94 LMNA (0.45) LMNAGPR84FFAR1MAPTLCK
SCHEMBL7752092 0.90 ALDH1A1 (0.47) LMNAGPR84
SCHEMBL7756102 0.89 LMNA (0.45) LMNAGPR84FFAR1MAPTLCK
SCHEMBL7756728 0.88 LMNA (0.45) LMNAGPR84FFAR1MAPTLCK
SCHEMBL7756660 0.88 ALDH1A1 (0.39) LMNAGPR84FFAR1MAPTLCK
SCHEMBL7752086 0.88 ALDH1A1 (0.48) LMNAGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470041-B1 Process for the preparation of a rubber having polymer bound functionality GOODYEAR TIRE & RUBBER (US) 1996-02-28 EP disclosed
US-5093517-A Catalyzed ester interchange THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-03 US disclosed
EP-0470041-A1 Process for the preparation of a rubber having polymer bound functionality THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-02-05 EP disclosed
US-5073592-A Oxidation resistant THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-12-17 US disclosed
EP-0282435-B1 IMPROVED METHOD FOR THE ESTERIFICATION OF THIOPROPIONATES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-10-16 EP disclosed
EP-0282435-A1 Improved method for the esterification of thiopropionates THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-09-14 EP disclosed
US-4298522-A HEAT AND AGING RESISTANCE NIPPON ZEON CO. LTD. (JP) 1981-11-03 US disclosed