Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.63 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.63 |
| ▸ | PARP1 | P09874 | 3/20 | 0.63 |
| ▸ | WNT3A | P56704 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SPR | P35270 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MTHFD2 | P13995 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032502 | 0.97 | TNKS2 (0.68) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL1033822 | 0.90 | TNKS2 (0.55) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL15661448 | 0.83 | HPGD (0.54) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL18689656 | 0.82 | SPR (0.70) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL1035001 | 0.81 | TNKS2 (0.68) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL17476968 | 0.81 | TNKS2 (0.69) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL14107495 | 0.80 | HTR2C (0.49) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL14344503 | 0.80 | MTHFD2 (0.49) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL15660095 | 0.80 | LMNA (0.57) | TNKSTNKS2PARP1WNT3AHPGD | |
| SCHEMBL7782092 | 0.79 | KMT2A (0.54) | TNKSTNKS2PARP1WNT3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696588-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5451565-A | 2-aryl-5,6-ring-fused pyrimidines and herbicidal use | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| US-5378678-A | 2-aryl-5,6-ring-fused pyrimidines and herbicidal use | ROHM AND HAAS COMPANY (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0579424-A1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |