Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070870 | 0.87 | RAB9A (0.53) | RAB9ANPC1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL9070887 | 0.85 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9070885 | 0.85 | ALDH1A1 (0.47) | RAB9ANPC1HSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL2667497 | 0.83 | SCD (0.52) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9070819 | 0.81 | RAB9A (0.47) | RAB9ANPC1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL9070821 | 0.80 | GCK (0.55) | — | |
| SCHEMBL9070830 | 0.77 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2667715 | 0.77 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2MAPTBRD4 | |
| SCHEMBL2667605 | 0.77 | NPC1 (0.48) | RAB9ANPC1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL9070824 | 0.75 | SMN1; SMN2 (0.44) | RAB9ANPC1HSD17B10SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |