Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070869 | 0.88 | RAB9A (0.51) | POLBKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9070824 | 0.85 | SMN1; SMN2 (0.44) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9070889 | 0.84 | RAB9A (0.44) | POLBKDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL9070888 | 0.81 | PIK3CA (0.47) | POLBKDM4ECYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL9070806 | 0.77 | RAB9A (0.43) | POLBKDM4EL3MBTL1MIFALDH1A1 | |
| SCHEMBL9070825 | 0.75 | GCK (0.56) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2667716 | 0.74 | KDM4E (0.48) | POLBKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9070885 | 0.74 | ALDH1A1 (0.47) | POLBKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9070886 | 0.74 | RAB9A (0.46) | POLBKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9070900 | 0.73 | RAB9A (0.55) | KDM4EL3MBTL1ALDH1A1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |